Ecotoxicology-on-a-chip

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Project Description

To quantify the effects of multiple physico-chemical stressors on the metabolism of single cells, this project combines microfluidic technology and quantitative phase imaging (QPI) into a novel high-throughput ‘Ecotoxicology-on-a-chip’ approach. The developed image analysis pipeline will enable us to determine growth rates and cell dry mass of marine bacteria on a single-cell level and thus, improve ecotoxicological predictions regarding pollutant effects in aquatic ecosystems.

Tags: Phase imaging microscopy, single cell analysis, mother machine