Amyotrophic lateral sclerosis

Illustration (click to hide): Amyotrophic lateral sclerosis

Project Description

Amyotrophic lateral sclerosis is a neurodegenerative disease characterized by the loss of motor neurons in the cortex brain stem and spinal chord. The incidence is 1 in 50 000 combining US and EU populations. The disease is fatal in approximately 5 years and there is currently no cure for AL. Morover, given the low incidence of case, finding new treatments for ALS is not a priority of the Pharma industry. At SciLifeLab, we are developing several image based assays to discover strategies that can alleviate the death of ALS-motor neurons.


Tags: Microscopy, cell biology

Project Information

  • BIIF Principal Investigators

    • Petter Ranefall
    • Carolina Wählby

    External Authors

    Jordi Carreras Puigvert, Oskar Fernandez-Capetillo - Division of Translational Medicine and Chemical Biology Department of Medical Biochemistry and Biophysics Karolinska Institutet, SciLifeLab, Stockholm

  • Date

    2016-01-13 🠚 2017-12-07