Identifying novel small molecule drugs for CCM treatment
Illustration (click to hide):
Project Description
We are identifying modulators of VE-cadherin formation in images generated in a small molecule drug screen. We use CellProfiler to detect and quantify changes, and KNIME for automated classification of the images and hit-detection.
Tags: Microscopy, cell biology
Project Information
BIIF Principal Investigators
Anna Klemm
Petter Ranefall
Carolina Wählby
External Authors
Joppe Oldenburg, Johan Brännström, Peetra Magnusson, Elisabetta Dejana, Uppsala University